Brittle Bones

Brittle bone disease (Steogenesis Imperfecta) is a rare, usually inherited disorder that causes weak and easily-breakable bones, usually due to low production of collagen. There is no cure for brittle bones. Treatment typically focuses on stopping progression of this problem, and decreasing patient discomfort.

There are six different types of brittle bone disease.

• Type I brittle bone disease - the most frequently occurring and the least severe disease causing brittle bones. Type I brittle bone disease patients are prone to scoliosis, poor muscle tone and weak joints.
• Type II brittle bone disease - extremely severe bone deformation and respiratory problems, with most affected children dying before age one
• Type III brittle bone disease - occurs when the body produces poor quality collagen. Children show progressive symptoms as they age, causing significant deformity and disability
• Type IV brittle bone disease - characterized by poor quality collagen but tends to be a milder problem